Searchable abstracts of presentations at key conferences in endocrinology

ea0090p265 | Late-Breaking | ECE2023

Genetic profile of bone metabolism and immunity modulators in bone metastasis in castration-resistant prostate cancer

Janeiro Matthew , Matos Andreia , Medeiros Rui , Bicho Manuel , Ribeiro Ricardo

Introduction: Prostate cancer is a neoplasm with high incidence and prevalence in the elderly population in western countries. Androgen deprivation therapy (ADT) has been used in locally advanced or metastatic disease, although most relapse, becoming hormone resistant, which is a poor prognostic event.Objectives: The aim of this study was to evaluate the association of genetic polymorphisms NOS2, GPRC6A, VKORC1, ARGI and ARGII in prostate cancer, particu...